Adaptive Trial Design and Learning Evaluation: Methods for PCOR and Quality Improvement Assessment

The AHRQ’s Practice-Based Research Network Resource Center hosted a research methodology webinar on August 18, 2015 from 12:30-2:00 PM EDT.  Presenters discussed the minimum standards recommended for the design, conduct, and reporting of adaptive clinical trials as applied to patient-centered outcomes research (PCOR). A detailed overview of how to apply the learning evaluation approach to quality improvement assessments across multiple organizations was also discussed.

This Live series activity, AHRQ Practice-Based Research Network Resource Center National Webinars, from 09/10/2014 - 09/10/2015, has been reviewed and is acceptable for credit by the American Academy of Family Physicians. Physicians should claim only the credit commensurate with the extent of their participation in the activity. This webinar has been approved for 1.25 elective CME credit(s).

Critical Reference Material:

• Balasubramanian BA, Cohen DJ, Davis MM, et al. Learning Evaluation: blending quality improvement and implementation research methods to study healthcare innovations. Implement Sci 2015;10(31):015-0219. PMID: 25889831.
• Detry MA, Lewis RJ, Broglio KR, et al. Standards for the Design, Conduct, and Evaluation of Adaptive Randomized Clinical Trials. Patient-Centered Outcomes Research Institute. 2012 March:i-55. (PDF - 381.56 KB)
• Kairalla J, Coffey C, Thomann MA, et al. Trials 2012 August;13(145):1-9. PMID: 22917111. (PDF - 303.72 KB)
• Cohen DJ, Leviton LC, Isaacson N, et al. Online Diaries for Qualitative Evaluation: Gaining Real-Time Insights. Am J Eval 2006; 27:163-84.
• Cohen DJ, Balasubramanian BA, Davis M, et al. Integrating Behavioral Health and Primary Care: Consulting, Coordinating and Collaborating Among Professionals. J Am Board Fam Med 2015 September-October; 28:S21-S3. doi:10.3122/jabfm.2015.S1.150042. (PDF - 148.28 KB)
• The AHRQ PBRN Resource Center Guidance Document on Rapid-Cycle Research, Using Rapid-Cycle Research to Reach Goals: Awareness, Assessment, Adaptation, Acceleration, available at: https://pbrn.ahrq.gov/tools-and-resources under the section “New Resources!”

 Event Materials:

• Presentation Slides (PDF - 1,019 KB)