Centers for Primary Care Practice-Based Research and Learning: Nurture Partnerships, Method Development, and Trans-Network Collaborations

In September 2012, AHRQ funded 5-year grants to establish eight Centers for Primary Care Practice-Based Research and Learning (P30 Center Grants).  Each Center has a unique purpose and focus, but all share common features and goals with the ultimate aim of improving patient care to:

  • bring together multiple PBRNs to stimulate innovation in improving the delivery and organization of primary care
  • nurture partnerships
  • conduct research
  • disseminate knowledge 

For a one-stop, comprehensive overview of the P30 program, including more information on the resources P30s have to offer and about trans-P30 collaborations, access the P30 Centers Overview Profile (PDF – 1.24 MB).  Below we provide a brief description of each of the P30 Centers and links to their full summaries. 


CoCoNet2: Coordinated Coalition of Primary Care Research Networks (PDF - 2.51 MB)

The CoCoNet2 Center is an active learning community, sharing resources and collaborating on research projects among six PBRNs serving thousands of patients from all socioeconomic, racial, and ethnic groups. All member PBRNs employ practice facilitators  and have expertise in implementation and quality improvement.

COIN: Collaborative Ohio Inquiry Network (PDF - 339 KB)

COIN’s mission is to develop the capacity of PBRNs, to do practice-based research by stimulating and fostering research collaborations, and to disseminate research findings by effectively sharing knowledge and translating research into practice.

C-PRL: National Center for Pediatric Practice Based Research and Learning (PDF – 1.11 MB)

The National Center for Pediatric Practice Based Research and Learning (C-PRL) brings together partners that put child-based research first and facilitate robust research projects in the areas of Health Information Technology and Meaningful Use, including work on patient engagement and using data to guide research.

Meta-LARC: Meta-network Learning and Research Center (PDF – 571 KB)

Meta-LARC provides a robust infrastructure capable of managing large clinical trials and practice transformation initiatives. The size of the consortium and partnerships with institutional Clinical and Translational Science Award (CTSA) programs facilitates a broad range of Health Information Technology and Meaningful Use projects.

MOSAIC: Meaningful Outcomes and Science to Advance Innovations Center of Excellence (PDF – 522 KB)

MOSAIC combines the efforts of over a dozen PBRNs and other partners, such as the American Academy of Family Physicians and the DARTNet Institute, to advance the field of health information technology and Meaningful Use, engage patients in practice-based research, and provide support to new researchers to ensure the field of practice-based research continues to evolve and be vibrant.

N2: Building a Network of Safety Net PBRNs (PDF – 576 KB)

N2 is a network of safety-net PBRNs dedicated to serving the underrepresented and developing fruitful relationships with the community health centers that serve its target population. Projects such as Collaborative Care to Reduce Depression and Increase Cancer Screening among Low-Income Urban Women (PCM3) and Enhancing Community Health Center Based Patient Centered Outcomes Research (EnCoRE) highlight this focus.

PPRNet: Primary (Care) Practice Research Network (PDF – 804 KB)

PPRNet works with its member practices to improve health care and conduct research important to the entire primary health care system. All PPRNet practices use electronic health records (EHRs) and many long-time members are pioneers in EHR use.

PRIME Net: Primary Care MultiEthnic Network Center in Practice-Based Research and Learning (PDF – 417 KB)

PRIME Net is a consortium of geographically diverse PBRNs that engage diverse primary care patients in practice-based research. For example, several member networks came together to partner with their communities to develop best practices for participation in research and PRIME Net member San Francisco Bay Collaborative Research Network led a project to develop multilingual prescription instructions patients with limited English proficiency.