Symptoms of depression and anxiety and adherence to antihypertensive medication

Journal Name: 
Am J Hypertens
Authors: 
Bautista,L.E.
Vera-Cala,L.M.
Colombo,C.
Smith,P.
Abstract: 
BACKGROUND: Nonadherence to drug treatment is a major contributor to antihypertensive treatment failure. Mood disorders could impair the patient's desire and ability to follow physician's recommendations. We evaluated the role of symptoms of depression and anxiety on adherence to antihypertensive drug treatment. METHODS: We conducted a longitudinal cohort study in 20-70 years old patients starting antihypertensive drug treatment, without other chronic conditions, and not taking mood-modifying drugs. Severity of symptoms of depression and anxiety were evaluated at enrollment and 3, 6, 9, and 12 months of follow-up, using the Beck depression inventory-II (BDI-II) and the psychological general well-being index (PGWB), respectively. Treatment adherence was measured by pill count. Nonadherence was defined as taking /=14) and those with at least mild anxiety (PGWB anxiety score
4
2012
Volume: 
25
Pages: 
505-511
Keywords: 
2070, 50, adherence, Anxiety, Cohort Studies, Depression, disorders, electronic, factors, Health, intervention, Male, Methods, Mood Disorders, patient, Patients, population, regression, Research, Research Support, Risk, Risk Factors, Role, support, Time, Treatment Failure, Universities, Wisconsin